組蛋白去乙醯酶3（Histone Deacetylase 3）抑制劑篩選套組
【供應廠商】萊恩生物科技有限公司
【公司電話】04-2523-9639
【業務專員】陳俊豪 0937-229803
【電子信箱】biolion0819@gmail.com
HDAC3 Inhibitor Screening Kit
Catalog#: K363-100 | Size: 100 assays
Catalog#: K363-100 | Size: 100 assays
Kit Summary:
• Detection method- Fluorescence (Em/Ex = 380/500 nm)
• Sample type- Testing candidate HDAC3 inhibitors
• Applications- Suitable for high throughput screening of HDAC3 inhibitors
• Detection method- Fluorescence (Em/Ex = 380/500 nm)
• Sample type- Testing candidate HDAC3 inhibitors
• Applications- Suitable for high throughput screening of HDAC3 inhibitors
Features & Benefits:
• Simple procedure; takes ~ 60 min
• Fast and convenient
• Kit contains the necessary reagents for testing putative HDAC3 inhibitors
• Simple procedure; takes ~ 60 min
• Fast and convenient
• Kit contains the necessary reagents for testing putative HDAC3 inhibitors
Kit Components:
• HDAC3 Assay Buffer
• HDAC3 Substrate
• HDAC-3 Enzyme
• Developer
• Trichostatin A
• HDAC3 Assay Buffer
• HDAC3 Substrate
• HDAC-3 Enzyme
• Developer
• Trichostatin A
Description:
Histone deacetylases (HDACs) represent a large family of enzymes identified as key regulators of nucleosomal histone acetylation, a major event that controls eukaryotic gene transcription and are classified into three groups. They are believed to be involved in important biological activities, such as cell differentiation, proliferation, apoptosis, and senescence. In BioVision’s HDAC-3 Inhibitor screening Kit, HDAC-3 and developer will deacetylate and cleave the substrate [Arg-His-Lys-Lys(Ac)-AFC] to release the quenched fluorescent group (AFC), which can be detected at Em/Ex=380/500 nm. In presence of a HDAC-3 inhibitor, the cleavage will be inhibited. The kit provides a rapid, simple, sensitive, and reliable test, which is also suitable for high throughput screening of HDAC-3 inhibitors. Trichostatin A (TSA) is included as a control inhibitor to compare the efficacy of the test inhibitors.
Histone deacetylases (HDACs) represent a large family of enzymes identified as key regulators of nucleosomal histone acetylation, a major event that controls eukaryotic gene transcription and are classified into three groups. They are believed to be involved in important biological activities, such as cell differentiation, proliferation, apoptosis, and senescence. In BioVision’s HDAC-3 Inhibitor screening Kit, HDAC-3 and developer will deacetylate and cleave the substrate [Arg-His-Lys-Lys(Ac)-AFC] to release the quenched fluorescent group (AFC), which can be detected at Em/Ex=380/500 nm. In presence of a HDAC-3 inhibitor, the cleavage will be inhibited. The kit provides a rapid, simple, sensitive, and reliable test, which is also suitable for high throughput screening of HDAC-3 inhibitors. Trichostatin A (TSA) is included as a control inhibitor to compare the efficacy of the test inhibitors.
Storage Conditions:
-20°C (Upon receipt place HDAC-3 Enzyme at -80 °C for storage.)
-20°C (Upon receipt place HDAC-3 Enzyme at -80 °C for storage.)
Shipping Conditions:
gel pack
gel pack
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